Mechanisms of hypoxia signalling: new implications for nephrology

Studies of the regulation of erythropoietin (EPO) production by the liver and kidneys, one of the classical physiological responses to hypoxia, led to the discovery of human oxygen-sensing mechanisms, which are now being targeted therapeutically. The oxygen-sensitive signal is generated by 2-oxoglut...

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Bibliographic Details
Main Authors: Schödel, J, Ratcliffe, P
Format: Journal article
Language:English
Published: Springer Nature 2019