Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population.
AIMS/HYPOTHESIS: ATP-sensitive potassium (K(ATP)) channels are crucial for the regulation of insulin secretion from pancreatic beta cells and mutations in either the Kir6.2 or SUR1 subunit of this channel can cause congenital hyperinsulinism (CHI). The aim of this study was to analyse the functional...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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