APE1-dependent repair of DNA single-strand breaks containing 3'-end 8-oxoguanine.

DNA single-strand breaks containing 3'-8-oxoguanine (3'-8-oxoG) ends can arise as a consequence of ionizing radiation and as a result of DNA polymerase infidelity by misincorporation of 8-oxodGMP. In this study we examined the mechanism of repair of 3'-8-oxoG within a single-strand br...

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Bibliographic Details
Main Authors: Parsons, J, Dianova, I, Dianov, G
Format: Journal article
Language:English
Published: 2005