Whole genome sequencing coupled to imputation discovers genetic signals for anthropometric traits

Deep sequence-based imputation can enhance the discovery power of genome-wide association studies by assessing previously unexplored variation across the common- and low-frequency spectra. We applied a hybrid whole genome sequencing (WGS) and deep imputation approach to examine the broader allelic a...

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Bibliographic Details
Main Authors: Tachmazidou, I, Süveges, D, Min, J, Rayner, N, Southam, L, McCarthy, M, Lindgren, C, Morris, A, SpiroMeta consortium, GoT2D consortium, arcOGEN consortium, Understanding Society Scientific Group, UK10K consortium
Format: Journal article
Published: Elsevier 2017