NMDA receptor subunit NR2A is required for rapidly acquired spatial working memory but not incremental spatial reference memory.

NMDA receptors (NMDARs) containing NR2A (epsilon1) subunits are key contributors to hippocampal long-term potentiation (LTP) induction in adult animals and have therefore been widely implicated in hippocampus-dependent spatial learning. Here we show that mice lacking the NR2A subunit or its C-termin...

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Bibliographic Details
Main Authors: Bannerman, D, Niewoehner, B, Lyon, L, Romberg, C, Schmitt, W, Taylor, A, Sanderson, D, Cottam, J, Sprengel, R, Seeburg, P, Köhr, G, Rawlins, J
Format: Journal article
Language:English
Published: 2008