Highly stereoselective intermolecular oxy-michael addition reaction to alpha,beta-unsaturated malonate esters.

[reaction: see text] The highly diastereoselective oxy-Michael addition of the "naked" anion of (6S)-methyl delta lactol to alkylidiene-, arylidene-, and heteroarylidenemalonate derivatives leading to the direct formation of THP-protected beta-hydroxy ester derivatives is described. Subseq...

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Detalles Bibliográficos
Main Authors: Buchanan, D, Dixon, D, Hernandez-Juan, F
Formato: Journal article
Idioma:English
Publicado: 2004