Embryonic Tbx3+ cardiomyocytes form the mature cardiac conduction system by progressive fate restriction

A small network of spontaneously active Tbx3+ cardiomyocytes forms the cardiac conduction system (CCS) of the heart. Understanding the origin and mechanism of development of the CCS network are important steps towards disease modeling and biological pacemaker development to treat arrhythmias. We fou...

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Những tác giả chính: Mohan, R, Mommersteeg, M, Domínguez, J, Choquet, C, Wakker, V, De Gier-De Vries, C, Boink, G, Boukens, B, Miquerol, L, Verkerk, A, Christoffels, V
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Company of Biologists: Development 2018