Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins.
Clinical experience with adenovirus vectors has highlighted the need for improved delivery and targeting. Tumour-associated endothelium offers an additional mechanism for enhanced viral uptake into tumours which is accessible for systemic gene delivery. Building on expertise in using polymer 's...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2011
|