Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins.

Clinical experience with adenovirus vectors has highlighted the need for improved delivery and targeting. Tumour-associated endothelium offers an additional mechanism for enhanced viral uptake into tumours which is accessible for systemic gene delivery. Building on expertise in using polymer 's...

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Bibliographic Details
Main Authors: Bachtarzi, H, Stevenson, M, Šubr, V, Ulbrich, K, Seymour, L, Fisher, K
Format: Journal article
Language:English
Published: 2011