MeCP2 repression goes nonglobal

Eitemau Tebyg

• MeCP2 binding to DNA depends upon hydration at methyl-CpG.
  gan: Ho, K, et al.
  Cyhoeddwyd: (2008)
• The molecular basis of MeCP2 function in the brain
  gan: Tillotson, R, et al.
  Cyhoeddwyd: (2019)
• MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex.
  gan: Klose, R, et al.
  Cyhoeddwyd: (2004)
• DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG.
  gan: Klose, R, et al.
  Cyhoeddwyd: (2005)
• MeCP2 represses the activity of topoisomerase IIβ in long neuronal genes
  gan: Sabin A. Nettles, et al.
  Cyhoeddwyd: (2023-12-01)