Molecular and behavioural characterisation of novel alpha-synuclein BAC transgenic mouse models of Parkinson's disease
<p>Alterations in the expression levels of α-synuclein (<em>SNCA</em>) provide an important link between familial and sporadic forms of Parkinson’s disease (PD). Multiplications of the human wild-type SNCA locus give rise to early-onset autosomal-dominant forms of PD and elevated α...
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| Format: | Thesis |
| Language: | English |
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2013
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