A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.
Endotoxin tolerance is characterized by the suppression of further TNF release upon recurrent exposure to LPS. This phenomenon is proposed to act as a homeostatic mechanism preventing uncontrolled cytokine release such as that observed in bacterial sepsis. The regulatory mechanisms and interindividu...
Κύριοι συγγραφείς: | Fairfax, B, Davenport, E, Makino, S, Hill, A, Vannberg, F, Knight, J |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2011
|
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance
ανά: Taylor, PC, κ.ά.
Έκδοση: (2024) -
Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression
ανά: Mario M. Müller, κ.ά.
Έκδοση: (2017-04-01) -
An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6.
ανά: Fairfax, B, κ.ά.
Έκδοση: (2010) -
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles
ανά: Fairfax, B, κ.ά.
Έκδοση: (2012) -
Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles.
ανά: Fairfax, B, κ.ά.
Έκδοση: (2012)