A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.

A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance.

Endotoxin tolerance is characterized by the suppression of further TNF release upon recurrent exposure to LPS. This phenomenon is proposed to act as a homeostatic mechanism preventing uncontrolled cytokine release such as that observed in bacterial sepsis. The regulatory mechanisms and interindividu...

书目详细资料
Main Authors:	Fairfax, B, Davenport, E, Makino, S, Hill, A, Vannberg, F, Knight, J
格式:	Journal article
语言:	English
出版:	2011

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