Genomic analysis reveals a common breakpoint in amplifications of the Plasmodium vivax multidrug resistance 1 locus in Thailand

In co-endemic regions where mefloquine is used to treat Plasmodium falciparum, drug pressure may select for mefloquine-resistant P. vivax mediated by increased copy number of the multidrug resistance 1 gene (pvmdr1). Surveillance is not undertaken routinely owing in part to methodological challenges...

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Bibliographic Details
Main Authors: Auburn, S, Serre, D, Pearson, R, Amato, R, Sriprawat, K, To, S, Handayuni, I, Suwanarusk, R, Russell, B, Drury, E, Stalker, J, Miotto, O, Kwiatkowski, D, Nosten, F, Price, R
Format: Journal article
Language:English
Published: Oxford University Press 2016