Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma

Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma

<br><strong>Objective: </strong>Current strategies to guide selection of neoadjuvant therapy in oesophageal adenocarcinoma (OAC) are inadequate. We assessed the ability of a DNA damage immune response (DDIR) assay to predict response following neoadjuvant chemotherapy in OAC.</b...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Turkington, RC, Knight, LA, Blayney, JK, Secrier, M, Douglas, R, Parkes, EE, Sutton, EK, Stevenson, L, McManus, D, Halliday, S, McCavigan, AM, Logan, GE, Walker, SM, Steele, CJ, Perner, J, Bornschein, J, MacRae, S, Miremadi, A, McCarron, E, McQuaid, S, Arthur, K, James, JA, Eatock, MM, O'Neill, R, Noble, F, Underwood, TJ, Harkin, DP, Salto-Tellez, M, Fitzgerald, RC, Kennedy, RD, Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Study Group
Format: Journal article
Sprache:English
Veröffentlicht: BMJ Publishing Group 2019

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