Analysis of extrachromosomal structures containing human centromeric alphoid satellite DNA sequences in mouse cells.
Yeast artificial chromosomes (YACs) spanning the centromeric region of the human Y chromosome were introduced into mouse LA-9 cells by spheroplast fusion in order to determine whether they would form mammalian artificial chromosomes. In about 50% of the cell lines generated, the YAC DNA was associat...
Hlavní autoři: | , , |
---|---|
Médium: | Journal article |
Jazyk: | English |
Vydáno: |
1996
|