Analysis of extrachromosomal structures containing human centromeric alphoid satellite DNA sequences in mouse cells.
Yeast artificial chromosomes (YACs) spanning the centromeric region of the human Y chromosome were introduced into mouse LA-9 cells by spheroplast fusion in order to determine whether they would form mammalian artificial chromosomes. In about 50% of the cell lines generated, the YAC DNA was associat...
Autori principali: | Taylor, S, Larin, Z, Tyler-Smith, C |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
1996
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