Intramembrane proteolysis by rhomboids: catalytic mechanisms and regulatory principles.

Rhomboids are intramembrane serine proteases that cleave membrane proteins within the bilayer, and which control a wide variety of biological processes. Recent structures of Escherichia coli rhomboids in complex with mechanism-based inhibitors provide insight into their catalytic mechanism. The inhi...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Vinothkumar, K, Freeman, M
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2013