Intramembrane proteolysis by rhomboids: catalytic mechanisms and regulatory principles.
Rhomboids are intramembrane serine proteases that cleave membrane proteins within the bilayer, and which control a wide variety of biological processes. Recent structures of Escherichia coli rhomboids in complex with mechanism-based inhibitors provide insight into their catalytic mechanism. The inhi...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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