Intramembrane proteolysis by rhomboids: catalytic mechanisms and regulatory principles.

Rhomboids are intramembrane serine proteases that cleave membrane proteins within the bilayer, and which control a wide variety of biological processes. Recent structures of Escherichia coli rhomboids in complex with mechanism-based inhibitors provide insight into their catalytic mechanism. The inhi...

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Những tác giả chính: Vinothkumar, K, Freeman, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2013