Exploring the effects of nutrient deprivation and waste accumulation on T cells and oncolytic adenoviruses; in order to create immune activators for tumour therapy
<p>High metabolic stress is a hallmark of cancer. Tumours are characterised by a depletion of amino acids and accumulation of lactic acid, both promote an immunosuppressive milieu and may limit success of cancer immunotherapy. One such therapeutic approach is represented by an oncolytic adenov...
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| Format: | Thesis |
| Language: | English |
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2020
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