Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis
A 13-step, highly stereoselective synthesis of (-)-nakadomarin A has been achieved using the combination of a bifunctional organocatalyst controlled Michael addition, a nitro-Mannich/lactamization cascade, an alkyne ring-closing metathesis/syn-reduction, and furan/iminium ion cyclization/reduction a...
Glavni autori: | , , , |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2011
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