Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis
A 13-step, highly stereoselective synthesis of (-)-nakadomarin A has been achieved using the combination of a bifunctional organocatalyst controlled Michael addition, a nitro-Mannich/lactamization cascade, an alkyne ring-closing metathesis/syn-reduction, and furan/iminium ion cyclization/reduction a...
| Główni autorzy: | , , , |
|---|---|
| Format: | Journal article |
| Język: | English |
| Wydane: |
2011
|
| _version_ | 1826265719626530816 |
|---|---|
| author | Jakubec, P Kyle, A Calleja, J Dixon, D |
| author_facet | Jakubec, P Kyle, A Calleja, J Dixon, D |
| author_sort | Jakubec, P |
| collection | OXFORD |
| description | A 13-step, highly stereoselective synthesis of (-)-nakadomarin A has been achieved using the combination of a bifunctional organocatalyst controlled Michael addition, a nitro-Mannich/lactamization cascade, an alkyne ring-closing metathesis/syn-reduction, and furan/iminium ion cyclization/reduction as key steps. © 2011 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-06T20:28:05Z |
| format | Journal article |
| id | oxford-uuid:3013eaa2-2cb8-4134-9b35-2d4f29de7ec6 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:28:05Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:3013eaa2-2cb8-4134-9b35-2d4f29de7ec62022-03-26T12:59:25ZTotal synthesis of (-)-nakadomarin A: alkyne ring-closing metathesisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3013eaa2-2cb8-4134-9b35-2d4f29de7ec6EnglishSymplectic Elements at Oxford2011Jakubec, PKyle, ACalleja, JDixon, DA 13-step, highly stereoselective synthesis of (-)-nakadomarin A has been achieved using the combination of a bifunctional organocatalyst controlled Michael addition, a nitro-Mannich/lactamization cascade, an alkyne ring-closing metathesis/syn-reduction, and furan/iminium ion cyclization/reduction as key steps. © 2011 Elsevier Ltd. All rights reserved. |
| spellingShingle | Jakubec, P Kyle, A Calleja, J Dixon, D Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis |
| title | Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis |
| title_full | Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis |
| title_fullStr | Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis |
| title_full_unstemmed | Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis |
| title_short | Total synthesis of (-)-nakadomarin A: alkyne ring-closing metathesis |
| title_sort | total synthesis of nakadomarin a alkyne ring closing metathesis |
| work_keys_str_mv | AT jakubecp totalsynthesisofnakadomarinaalkyneringclosingmetathesis AT kylea totalsynthesisofnakadomarinaalkyneringclosingmetathesis AT callejaj totalsynthesisofnakadomarinaalkyneringclosingmetathesis AT dixond totalsynthesisofnakadomarinaalkyneringclosingmetathesis |