Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo.

The extent of human memory T cell proliferation, differentiation, and telomere erosion that occurs after a single episode of immune challenge in vivo is unclear. To investigate this, we injected tuberculin purified protein derivative (PPD) into the skin of immune individuals and isolated responsive...

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Bibliographic Details
Main Authors: Reed, JR, Vukmanovic-Stejic, M, Fletcher, J, Soares, M, Cook, J, Orteu, C, Jackson, SE, Birch, K, Foster, G, Salmon, M, Beverley, P, Rustin, M, Akbar, A
Format: Journal article
Language:English
Published: 2004