Effect of metyrapone on the pituitary-adrenal axis in depression: relation to dexamethasone suppressor status.

It has been suggested that the well-documented hypercortisolaemia found in a proportion of patients with severe depression occurs either in response to excessive secretion of corticotrophin-releasing hormone-41 (CRH-41) from the hypothalamus, or as a consequence of up-regulation of pituitary CRH-41...

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Détails bibliographiques
Auteurs principaux: Ur, E, Dinan, T, O'Keane, V, Clare, A, McLoughlin, L, Rees, L, Turner, T, Grossman, A, Besser, G
Format: Journal article
Langue:English
Publié: 1992