Effect of metyrapone on the pituitary-adrenal axis in depression: relation to dexamethasone suppressor status.
It has been suggested that the well-documented hypercortisolaemia found in a proportion of patients with severe depression occurs either in response to excessive secretion of corticotrophin-releasing hormone-41 (CRH-41) from the hypothalamus, or as a consequence of up-regulation of pituitary CRH-41...
Main Authors: | Ur, E, Dinan, T, O'Keane, V, Clare, A, McLoughlin, L, Rees, L, Turner, T, Grossman, A, Besser, G |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1992
|
Similar Items
-
Opiate modulation of the pituitary-adrenal axis: effects of stress and circadian rhythm.
by: Grossman, A, et al.
Published: (1982) -
The pituitary-adrenal response to CRF-41 is unaltered by intravenous somatostatin in normal subjects.
by: Stafford, P, et al.
Published: (1989) -
Hyperactivity of the hypothalamo-pituitary-adrenal axis in obesity: a study of ACTH, AVP, beta-lipotrophin and cortisol responses to insulin-induced hypoglycaemia.
by: Weaver, J, et al.
Published: (1993) -
Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome.
by: Verhelst, J, et al.
Published: (1991) -
Adrenergic stimulation of the human pituitary-adrenal axis is attenuated by an analog of met-enkephalin.
by: Delitala, G, et al.
Published: (1991)