Learning alternative RNA splicing with applications to mutagenesis

Alternative RNA splicing is the process by which a single gene generates a large diversity of transcripts, but how the DNA sequence results in particular transcript abundances remains incompletely known. We present a two-stage machine learning algorithm that models this process by predicting the fre...

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Bibliographic Details
Main Author: Sanders, E
Other Authors: Hughes, J
Format: Thesis
Language:English
Published: 2022