Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators.

Παρόμοια τεκμήρια

• NF-kappaB-inducing kinase is dispensable for activation of NF-kappaB in inflammatory settings but essential for lymphotoxin beta receptor activation of NF-kappaB in primary human fibroblasts.
  ανά: Smith, C, κ.ά.
  Έκδοση: (2001)
• Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?
  ανά: Feldmann, M, κ.ά.
  Έκδοση: (2002)
• Antigen-specific T-cell downregulation by human dendritic cells following blockade of NF-kappaB.
  ανά: Calder, V, κ.ά.
  Έκδοση: (2003)
• Effective antigen presentation by dendritic cells is NF-kappaB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines.
  ανά: Yoshimura, S, κ.ά.
  Έκδοση: (2001)
• Activation of NF-kappaB by the intracellular expression of NF-kappaB-inducing kinase acts as a powerful vaccine adjuvant.
  ανά: Andreakos, E, κ.ά.
  Έκδοση: (2006)