Increased levels of CD4 T-cell activation in individuals with CXCR4 using viruses in primary HIV-1 infection.

CXCR4-tropic (X4) HIV-1 variants are associated with faster disease progression compared with CCR5-tropic variants; however, the mechanism for this is unclear. We measured T-cell activation in 120 individuals with primary HIV-1 infection. X4-utilizing variants, determined genotypically, were present...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Hamlyn, E, Hickling, S, Porter, K, Frater, J, Phillips, R, Robinson, M, Mackie, N, Kaye, S, McClure, M, Fidler, S
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2012