Unravelling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis

B-cell acute lymphoblastic leukemia is the commonest childhood cancer. In infants, B-cell acute lymphoblastic leukemia remains fatal, especially in patients with t(4;11), present in ~80% of cases. The pathogenesis of t(4;11)/KMT2A-AFF1+ (MLL-AF4+) infant B-cell acute lymphoblastic leukemia remains d...

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Bibliographic Details
Main Authors: Agraz-Doblas, A, Bueno, C, Bashford-Rogers, R, Roy, A, Schneider, P, Bardini, M, Ballerini, P, Cazzaniga, G, Moreno, T, Revilla, C, Gut, M, Valsecchi, MG, Roberts, I, Pieters, R, De Lorenzo, P, Varela, I, Menendez, P, Stam, RW
Format: Journal article
Language:English
Published: Ferrata Storti Foundation 2019