Niche-specific genome degradation and convergent evolution shaping Staphylococcus aureus adaptation during severe infections

During severe infections, Staphylococcus aureus moves from its colonising sites to blood and tissues, and is exposed to new selective pressures, thus potentially driving adaptive evolution. Previous studies have shown the key role of the agr locus in S. aureus pathoadaptation, however a more compreh...

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Bibliographic Details
Main Authors: Giulieri, SG, Guérillot, R, Duchene, S, Young, BC, Wilson, DJ
Format: Journal article
Language:English
Published: eLife Sciences Publications 2022