Localized hypermutation is the major driver of meningococcal genetic variability during persistent asymptomatic carriage

Host persistence of bacteria is facilitated by mutational and recombinatorial processes that counteract loss of genetic variation during transmission and selection from evolving host responses. Genetic variation was investigated during persistent asymptomatic carriage of Neisseria meningitidis. Inte...

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Bibliographic Details
Main Authors: Green, LR, Al-Rubaiawi, AA, Al-Maeni, MARM, Harrison, OB, Blades, M, Oldfield, NJ, Turner, DPJ, Maiden, MCJ, Bayliss, CD
Format: Journal article
Language:English
Published: American Society for Microbiology 2020