Evidence for a 5-HT6 receptor-mediated control of midbrain 5-HT neurons

Evidence for a 5-HT6 receptor-mediated control of midbrain 5-HT neurons

<p>The dorsal raphe nucleus (DRN) contains the majority of 5-hydroxytryptamine (5-HT)-producing neurons, whose firing is influenced by homeostatic feedback pathways. Dysfunction of 5-HT neurons is implicated in the pathophysiology of diseases such as depression. Thus, pathways regulating 5-HT...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक:	Brouard, J
अन्य लेखक:	Sharp, T
स्वरूप:	थीसिस
प्रकाशित:	2016

समान संसाधन

Conservation of 5-HT1A receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis
द्वारा: Naozumi eAraragi, और अन्य
प्रकाशित: (2013-08-01)

Evidence that 5-HT2 receptor agonist induced inhibtion of 5-HT cell firing is mediated by central and not peripheral 5-HT2 receptors
द्वारा: Boothman, L, और अन्य
प्रकाशित: (2003)

In vivo evidence that 5-HT(2C) receptors inhibit 5-HT neuronal activity via a GABAergic mechanism.
द्वारा: Boothman, L, और अन्य
प्रकाशित: (2006)

The effect of lithium on 5-HT-mediated neuroendocrine responses and platelet 5-HT receptors.
द्वारा: Glue, P, और अन्य
प्रकाशित: (1986)

A possible role for 5-HT2C receptors in postsynaptic feedback regulation of 5 HT neurones
द्वारा: Raley, J, और अन्य
प्रकाशित: (2006)

Electrophysiological evidence for 5-HT2 receptor-mediated control of 5-HT cell firing in the dorsal raphe nucleus of the anaesthetised rat
द्वारा: Boothman, L, और अन्य
प्रकाशित: (2001)

Control of amygdala circuits by 5-HT neurons via 5-HT and glutamate co-transmission
द्वारा: Sengupta, A, और अन्य
प्रकाशित: (2017)

5-HT(1B) receptor regulation of serotonin (5-HT) release by endogenous 5-HT in the substantia nigra.
द्वारा: Threlfell, S, और अन्य
प्रकाशित: (2010)

The Effect of Serotonin-Targeting Antidepressants on Neurogenesis and Neuronal Maturation of the Hippocampus Mediated via 5-HT1A and 5-HT4 Receptors
द्वारा: Eri Segi-Nishida
प्रकाशित: (2017-05-01)

5-HT1A and 5-HT2B receptor interaction and co-clustering regulate serotonergic neuron excitability
द्वारा: Amina Benhadda, और अन्य
प्रकाशित: (2023-08-01)

In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by midbrain-raphe nuclei: role of 5-HT1A receptors.
द्वारा: Hajós, M, और अन्य
प्रकाशित: (2003)

Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function.
द्वारा: Jennings, K, और अन्य
प्रकाशित: (2008)

Evidence that central 5-HT2A and 5-HT2B/C receptors regulate 5-HT cell firing in the dorsal raphe nucleus of the anaesthetised rat.
द्वारा: Boothman, L, और अन्य
प्रकाशित: (2003)

Expression of 5-HT receptors and the 5-HT transporter in rat brain after electroconvulsive shock.
द्वारा: Burnet, P, और अन्य
प्रकाशित: (1999)

5-HT Receptors and Temperature Homeostasis
द्वारा: Irina P. Voronova
प्रकाशित: (2021-12-01)

The role of 5-HT receptors in depression
द्वारा: Christine N. Yohn, और अन्य
प्रकाशित: (2017-06-01)

Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B.
द्वारा: Hughes, Z, और अन्य
प्रकाशित: (2007)

Existence of Brain 5‑HT1A–5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor–Receptor Interactions Regulating 5‑HT1A Receptor Recognition
द्वारा: Dasiel O. Borroto-Escuela, और अन्य
प्रकाशित: (2017-08-01)

Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction.
द्वारा: Daniel E Felsing, और अन्य
प्रकाशित: (2018-01-01)

Constitutively active 5-HT receptors: An explanation of how 5-HT antagonists inhibit gut motility in species where 5-HT is not a enteric neurotransmitter ?
द्वारा: Nick eSpencer
प्रकाशित: (2015-12-01)

5-HT6 receptor agonism facilitates emotional learning
द्वारा: Marcela ePereira, और अन्य
प्रकाशित: (2015-09-01)

Cellular mechanisms of the 5-HT7 receptor-mediated signaling
द्वारा: Daria eGuseva, और अन्य
प्रकाशित: (2014-10-01)

Slow wave sleep in humans: role of 5-HT2A and 5-HT2C receptors.
द्वारा: Sharpley, A, और अन्य
प्रकाशित: (1994)

Selective 5-HT1A and 5-HT2 receptor-mediated adrenocorticotropin release in the rat: effect of repeated antidepressant treatments.
द्वारा: Gartside, SE, और अन्य
प्रकाशित: (1992)

The distribution of 5-HT(6) receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT(6) receptor antagonist [(125)I]SB-258585.
द्वारा: Roberts, J, और अन्य
प्रकाशित: (2002)

Psychopharmacology of 5-HT(1A) receptors.
द्वारा: Cowen, P
प्रकाशित: (2000)

An RT-PCR study of 5-HT(6) and 5-HT(7) receptor mRNAs in the hippocampal formation and prefrontal cortex in schizophrenia.
द्वारा: East, S, और अन्य
प्रकाशित: (2002)

Anti-PTSD Effects of Hypidone Hydrochloride (YL-0919): A Novel Combined Selective 5-HT Reuptake Inhibitor/5-HT1A Receptor Partial Agonist/5-HT6 Receptor Full Agonist
द्वारा: Wen-Gang Liu, और अन्य
प्रकाशित: (2021-02-01)

Mediation of ACTH and prolactin responses to 5-HTP by 5-HT2 receptors.
द्वारा: Gartside, SE, और अन्य
प्रकाशित: (1990)

Further pharmacological characterization of 5-HT(2C) receptor agonist-induced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus in vivo.
द्वारा: Quérée, P, और अन्य
प्रकाशित: (2009)

Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels.
द्वारा: Licht, C, और अन्य
प्रकाशित: (2010)

Expression of mRNA for 5-HT2 Receptors and Proteins Related to Inactivation of 5-HT in Mouse Osteoblasts
द्वारा: Takao Hirai, और अन्य
प्रकाशित: (2009-01-01)

Effects of acute MDMA intoxication on mood and impulsivity: role of the 5-HT2 and 5-HT1 receptors.
द्वारा: Janelle H P van Wel, और अन्य
प्रकाशित: (2012-01-01)

Deletion of Munc18-1 in 5-HT neurons results in rapid degeneration of the 5-HT system and early postnatal lethality.
द्वारा: Jacobus J Dudok, और अन्य
प्रकाशित: (2011-01-01)

5-HT and anxiety.
द्वारा: Iversen, S
प्रकाशित: (1984)

5-HT2A and 5-HT2C receptors as hypothalamic targets of developmental programming in male rats
द्वारा: Malgorzata S. Martin-Gronert, और अन्य
प्रकाशित: (2016-04-01)

Mice over-expressing the 5-HT transporter show evidence of increased central 5-HT2A function
द्वारा: Jennings, K, और अन्य
प्रकाशित: (2003)

Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons.
द्वारा: Alberto Montalbano, और अन्य
प्रकाशित: (2015-01-01)

Schizophrenia and the 5-HT2A receptor gene.
द्वारा: Harrison, P, और अन्य
प्रकाशित: (1996)

Mice that over-express the 5-HT transporter show evidence of region-specific changes in 5-HT neurotransmission
द्वारा: Jennings, K, और अन्य
प्रकाशित: (2004)