Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signalling
The Hedgehog (HH) signalling pathway is a cell–cell communication system that controls the patterning of multiple tissues during embryogenesis in metazoans. In adults, HH signals regulate tissue stem cells and regenerative responses. Abnormal signalling can cause birth defects and cancer. The HH sig...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2019
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