Expression of the bcl-2 oncogene product and chromosomal translocation t(14;18) in Hodgkin's disease.
The B-cell lymphoma/leukemia oncogene bcl-2 takes part in crucial regulatory events in B-cell maturation and differentiation. The reciprocal chromosomal translocation t(14;18), leading to overexpression of this oncogene, can be found in the majority of follicular lymphomas and much less frequently i...
Main Authors: | , , , , , , |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
1992
|