Expression of the bcl-2 oncogene product and chromosomal translocation t(14;18) in Hodgkin's disease.
The B-cell lymphoma/leukemia oncogene bcl-2 takes part in crucial regulatory events in B-cell maturation and differentiation. The reciprocal chromosomal translocation t(14;18), leading to overexpression of this oncogene, can be found in the majority of follicular lymphomas and much less frequently i...
Prif Awduron: | Lorenzen, J, Hansmann, M, Pezzella, F, Hesse, C, Kneba, M, Gatter, K, Fischer, R |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
1992
|
Eitemau Tebyg
-
Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation.
gan: Pezzella, F, et al.
Cyhoeddwyd: (1990) -
Detection of 14;18 chromosomal translocation in paraffin-embedded lymphoma tissue.
gan: Pezzella, F, et al.
Cyhoeddwyd: (1989) -
Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma.
gan: Pezzella, F, et al.
Cyhoeddwyd: (1992) -
Bcl-2 protein expression in follicular lymphomas in absence of 14;18 translocation.
gan: Pezzella, F, et al.
Cyhoeddwyd: (1990) -
The bcl-2 gene and 14;18 translocation in lymphoproliferative disorders.
gan: Pezzella, F, et al.
Cyhoeddwyd: (1990)