SCAF4 and SCAF8, mRNA anti-terminator proteins

SCAF4 and SCAF8, mRNA anti-terminator proteins

Accurate regulation of mRNA termination is required for correct gene expression. Here, we describe a role for SCAF4 and SCAF8 as anti-terminators, suppressing the use of early, alternative polyadenylation (polyA) sites. The SCAF4/8 proteins bind the hyper-phosphorylated RNAPII C-terminal repeat doma...

Полное описание

Библиографические подробности
Главные авторы:	Gregersen, LH, Mitter, R, Ugalde, AP, Nojima, T, Proudfoot, NJ, Agami, R, Stewart, A, Svejstrup, JQ
Формат:	Journal article
Язык:	English
Опубликовано:	Cell Press 2019

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