Adipoyl-6-aminopenicillanic acid is a substrate for deacetoxycephalosporin C synthase (DAOCS)

Adipoyl-6-aminopenicillanic acid 5 was incubated with recombinant DAOCS and the resulting cephalosporin isolated. Adipoyl-6-aminopenicillanic acid 5 is approximately 735 times less efficient as a substrate for DAOCS in vitro (as judged by k(cat)/K(m)) than penicillin N 1.

Bibliographic Details
Main Authors: Shibata, N, Lloyd, MD, Baldwin, J, Schofield, C
Format: Journal article
Published: 1996