Apoptotic cell fragments locally activate tingible body macrophages in the germinal center

Germinal centers (GCs) that form within lymphoid follicles during antibody responses are sites of massive cell death. Tingible body macrophages (TBMs) are tasked with apoptotic cell clearance to prevent secondary necrosis and autoimmune activation by intracellular self antigens. We show by multiple...

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Bibliographic Details
Main Authors: Grootveld, AK, Kyaw, W, Panova, V, Lau, AWY, Ashwin, E, Seuzaret, G, Dhenni, R, Bhattacharyya, ND, Khoo, WH, Biro, M, Mitra, T, Meyer-Hermann, M, Bertolino, P, Tanaka, M, Hume, DA, Croucher, PI, Brink, R, Nguyen, A, Bannard, O, Phan, TG
Format: Journal article
Language:English
Published: Cell Press 2023