Two-pore channels: going with the flows

In recent years, our understanding of the structure, mechanisms and functions of the endo-lysosomal TPC (two-pore channel) family have grown apace. Gated by the second messengers, NAADP and PI(3,5)P2, TPCs are an integral part of fundamental signal-transduction pathways, but their array and plastici...

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Bibliographic Details
Main Authors: Morgan, AJ, Martucci, LL, Davis, LC, Galione, A
Format: Journal article
Language:English
Published: Portland Press 2022