Plagiarizing proteins: enhancing efficiency in asymmetric hydrogen-bonding catalysis through positive cooperativity.
A new twist for a fold: Conformationally well-defined thiourea catalysts, like that shown, stabilized by intramolecular hydrogen bonds demonstrate cooperative ligand-receptor binding. This conformation leads to significantly enhanced catalytic efficiency, resulting in higher turnover rates and lower...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2009
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