The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.

Nucleotide-binding and oligomerization domain (NOD)-like receptors constitute a first line of defense against invading bacteria. X-linked Inhibitor of Apoptosis (XIAP) is implicated in the control of bacterial infections, and mutations in XIAP are causally linked to immunodeficiency in X-linked lymp...

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Bibliographic Details
Main Authors:	Damgaard, R, Nachbur, U, Yabal, M, Wong, W, Fiil, B, Kastirr, M, Rieser, E, Rickard, J, Bankovacki, A, Peschel, C, Ruland, J, Bekker-Jensen, S, Mailand, N, Kaufmann, T, Strasser, A, Walczak, H, Silke, J, Jost, P, Gyrd-Hansen, M
Format:	Journal article
Language:	English
Published:	2012

The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.

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