Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children.

Cytotoxic T-lymphocyte (CTL) activity plays a central role in control of viral replication and in determining outcome in cases of human immunodeficiency virus type 1 (HIV-1) infection. Incorporation of important CTL epitope sequences into candidate vaccines is, therefore, vital. Most CTL studies hav...

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Bibliographic Details
Main Authors: Goulder, P, Brander, C, Annamalai, K, Mngqundaniso, N, Govender, U, Tang, Y, He, S, Hartman, K, O'Callaghan, C, Ogg, G, Altfeld, M, Rosenberg, E, Cao, H, Kalams, SA, Hammond, M, Bunce, M, Pelton, S, Burchett, SA, McIntosh, K, Coovadia, H, Walker, B
Format: Journal article
Language:English
Published: 2000