Ex-vivo whole blood cultures for predicting cytokine-release syndrome: dependence on target antigen and antibody isotype.

Ex-vivo whole blood assays have been evaluated for their ability to accurately predict the risk of a first-dose cytokine reaction developing in vivo following therapeutic antibody infusion. Tumour necrosis factor alpha (TNF alpha) release was rapidly detected in cultures incubated with either anti-C...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Wing, MG, Waldmann, H, Isaacs, J, Compston, D, Hale, G
Format: Journal article
Język:English
Wydane: 1995