Distinct recognition modes of FXXLF and LXXLL motifs by the androgen receptor.

Among nuclear receptors, the androgen receptor (AR) is unique in that its ligand-binding domain (LBD) interacts with the FXXLF motif in the N-terminal domain, resembling coactivator LXXLL motifs. We compared AR- and estrogen receptor alpha-LBD interactions of the wild-type AR FXXLF motif and coactiv...

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Bibliographic Details
Main Authors: Dubbink, H, Hersmus, R, Verma, C, van der Korput, H, Berrevoets, C, van Tol, J, Ziel-van der Made, A, Brinkmann, A, Pike, A, Trapman, J
Format: Journal article
Language:English
Published: 2004