SDH mutations in cancer.
The SDHA, SDHB, SDHC, SDHD genes encode the four subunits of succinate dehydrogenase (SDH; mitochondrial complex II), a mitochondrial enzyme involved in two essential energy-producing metabolic processes of the cell, the Krebs cycle and the electron transport chain. Germline loss-of-function mutatio...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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