Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.
The minimal signalling unit for tyrosine kinase receptors is two protomers dimerized by one or more ligands. However, it is clear that maximal signalling requires the formation of larger complexes of many receptors at discrete foci on the cell surface. The biological interactions that lead to this a...
Κύριοι συγγραφείς: | Harmer, N, Robinson, C, Adam, L, Ilag, L, Gallagher, J, Blundell, T |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2006
|
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex.
ανά: Harmer, N, κ.ά.
Έκδοση: (2004) -
Myocardial protection by heparin-based coacervate of FGF10
ανά: Zhouguang Wang, κ.ά.
Έκδοση: (2021-07-01) -
Crosstalk between Fibroblast Growth Factor (FGF) Receptor and Integrin through Direct Integrin Binding to FGF and Resulting Integrin-FGF-FGFR Ternary Complex Formation
ανά: Seiji Mori, κ.ά.
Έκδοση: (2013-08-01) -
Comparison of FGF-8, FGF-10, FGF-Receptor 2, Androgen Receptor, Estrogen Receptor-A and SS in Healthy and Hypospadiac Children
ανά: Emaratpardaz N, κ.ά.
Έκδοση: (2024-09-01) -
Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors
ανά: Mateusz Adam Krzyscik, κ.ά.
Έκδοση: (2017-07-01)