Silencing of Dok-7 in adult rat muscle increases susceptibility to passive transfer myasthenia gravis

Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies that target proteins at the neuromuscular junction, primarily the acetylcholine receptor (AChR) and the muscle-specific kinase. Because downstream of kinase 7 (Dok-7) is essential for the full activation of muscle-specific ki...

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Những tác giả chính: Gomez, A, Stevens, J, Mané-Damas, M, Molenaar, P, Duimel, H, Verheyen, F, Cossins, J, Beeson, D, De Baets, M, Losen, M, Martinez-Martinez, P
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Elsevier 2016