Silencing of Dok-7 in adult rat muscle increases susceptibility to passive transfer myasthenia gravis

Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies that target proteins at the neuromuscular junction, primarily the acetylcholine receptor (AChR) and the muscle-specific kinase. Because downstream of kinase 7 (Dok-7) is essential for the full activation of muscle-specific ki...

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Main Authors: Gomez, A, Stevens, J, Mané-Damas, M, Molenaar, P, Duimel, H, Verheyen, F, Cossins, J, Beeson, D, De Baets, M, Losen, M, Martinez-Martinez, P
格式: Journal article
语言:English
出版: Elsevier 2016