Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective studies

The only current strategy to test efficacy of novel interventions for sustained HIV control without antiretroviral therapy (ART) among people with HIV (PWH) is through an analytical treatment interruption (ATI). Inclusion of ‘placebo’ controls in ATIs poses ethical, logistical, and economic challeng...

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Main Authors: Gunst, JD, Gohil, J, Li, JZ, Bosch, RJ, White, Catherine Seamon, A, Chun, T, Mothe, B, Gittens, K, Praiss, L, De Scheerder, M, Vandekerckhove, L, Escandón, K, Thorkelson, A, Schacker, T, SenGupta, D, Brander, C, Papasavvas, E, Montaner, LJ, Martinez-Picado, J, Calin, R, Castagna, A, Muccini, C, de Jong, W, Leal, L, Tipoe, T, Frater, J
Format: Journal article
Language:English
Published: Nature Research 2025