T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM.
The peptide spanning residues 48-61 of hen egg white lysozyme (HEL) presented by I-A(k) gives rise to two T cell populations, referred to as type A and B, that distinguish the complex generated intracellularly upon processing of HEL from that formed with exogenous peptide. Here, we ascribe this diff...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2004
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