T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM.

The peptide spanning residues 48-61 of hen egg white lysozyme (HEL) presented by I-A(k) gives rise to two T cell populations, referred to as type A and B, that distinguish the complex generated intracellularly upon processing of HEL from that formed with exogenous peptide. Here, we ascribe this diff...

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Main Authors: Pu, Z, Lovitch, S, Bikoff, E, Unanue, E
格式: Journal article
语言:English
出版: 2004